One of the “enhancements” in Version 2.0 of Mozilla Firefox is the close-button on each and every tab that is open. While this makes it easy to close a specific tab, it makes it very difficult and slow to close many tabs in a row.
In V1.x, the close-button used to be at the right edge of the window, and to close 5 tabs, all you had to do is aim once and click five times. Now, since the size of the tabs is changing, you need to aim five times and click five times.
Here is a way to restore the old functionality:
There is detailed information about this configuration-item available at http://kb.mozillazine.org/Browser.tabs.closeButtons
Tab Mix Plus is a Firefox extention that may also be helpful with tabs.
Download it from here: https://addons.mozilla.org/firefox/1122/
Tab Mix Plus features help file can be found here: http://tmp.garyr.net/help/help.pdf